Docentes

Richard E. Frye. M.D., Ph.D. 
Neurólogo


Phoenix AZ - U.S.A.

Nneurólogo infantil con experiencia en trastornos del desarrollo neurológico y neurometabólico. Recibió un doctorado y un doctorado en fisiología y biofísica de la Universidad de Georgetown y completó su residencia y beca de neurología infantil en neurología conductual y discapacidades de aprendizaje en la Universidad de Harvard / Children's Hospital Boston.

Es autor de más de 150 publicaciones revisadas por pares y capítulos de libros, y es miembro de varios consejos editoriales. Ha realizado varios ensayos clínicos que demuestran la eficacia de tratamientos seguros y novedosos que se dirigen a las anormalidades fisiológicas subyacentes en niños con TEA. Es Jefe de Trastornos del Neurodesarrollo en el Instituto Neurológico de Barrow en el Phoenix Children's Hospital. 

Dr. Richard Frye is a Child Neurologist with expertise in neurodevelopmental and neurometabolic disorders. He received an MD and PhD in Physiology and Biophysics from Georgetown University and completed his Child Neurology Residency and Fellowship in Behavioral Neurology and Learning Disabilities at Harvard University/Children's Hospital Boston. He has authored over 150 peer-reviewed publications and book chapters, and serves on several editorial boards. He has conducted several clinical trials demonstrating the efficacy of safe and novel treatments that target underlying physiological abnormalities in children with ASD. He is the Chief of Neurodevelopmental Disorders at the Barrow Neurological Institute at Phoenix Children's Hospital.

Present Title

Professor of Child Health and Neurology
Director of Autism and Fragile X Programs
Chief, Division of Neurodevelopmental Disorders

Field of study

1982-86: B.A. - Psychobiology / Computer Science - Long Island University, Greenvale, NY
1988-91: M.S. - Biomedical Science/ Biostatistics - Drexel University, Philadelphia, PA
1991-98: Ph.D. - Physiology and Biophysics - Georgetown University, Washington, DC
1991-98: M.D. - Medicine - Georgetown University, Washington, DC

Postgraduate Training

5/1998-6/2000: Resident in Pediatrics, Jackson Memorial Hospital, University of Miami, Miami, FL
7/2000-6/2003: Resident in Neurology, Children's Hospital Boston, Harvard University, Boston, MA
7/2003-6/2005: Fellow in Behavioral Neurology and Learning Disabilities, Children's Hospital Boston, Harvard University, Boston, MA
7/2004-6/2005: Fellow in Psychology, Department of Psychology, Boston University, Boston, MA

Academic Appointments

7/2005-6/2006: Assistant Professor, Department of Pediatrics and Neurology,
University of Florida, Gainesville, FL
• 7/2005-6/2006: Co-Medical Director, Multidisciplinary Diagnostic and Training Program,
University of Florida, Gainesville, FL
• 1/2006-6/2006: Co-Director, University of Florida School Problems Clinic,
University of Florida, Gainesville, FL
• 7/2006-9/2011: Assistant Professor, Department of Pediatrics, Division of Child and Adolescent
Neurology and The Children's Learning Institute; Department of Neurology,
University of Texas, Houston, TX
• 1/2007-9/2011: Member, Center for Clinical and Translational Science, University of Texas,
Houston, TX
• 1/2007-9/2011: Director, Medically-Based Autism Clinic, Department of Pediatrics, University of Texas,
Houston, TX
 1/2010-9/2011: Director, Laboratory for the Biological Basis of Neurodevelopmental Disorders,
University of Texas, Houston, TX
 10/2011-12/2017: Associate Professor, Department of Pediatrics, University of Arkansas for Medical
Sciences, Little Rock, Arkansas
 10/2011-12/2017: Director of Autism Research, Arkansas Children's Hospital Research Institute,
Little Rock, Arkansas
 3/2012-12/2017: Neurology Consultant, Autism Treatment Network, University of Arkansas for
Medical Sciences, Little Rock, Arkansas
 6/2012-12/2017: Director, Autism Multispecialty Clinic, Arkansas Children's Hospital,
Little Rock, Arkansas
 10/2013-12/2017: Co-Director, Neurometabolic Clinic, Arkansas Children's Hospital,
Little Rock, Arkansas
• 8/2014-12/2017: Member, Center for Applied Research and Evaluation, Arkansas Children's Hospital,
Little Rock, Arkansas
• 1/2017-12/2017: Director, Neuroimmune Clinic, Arkansas Children's Hospital, Little Rock, Arkansas
• 12/2017-: Professor of Child Health,
University of Arizona College of Medicine - Phoenix, Phoenix AZ
 12/2017-: Chief, Section on Neurodevelopmental Disorders, Barrow Neurological Institute,
Phoenix Children's Hospital, Phoenix AZ
• 12/2017-: Director, Neurodevelopmental and Mitochondrial Disorders Research Laboratory,
University of Arizona College of Medicine - Phoenix, Phoenix AZ
 12/2017-: Director, Autism Program, Barrow Neurological Institute,
Phoenix Children's Hospital, Phoenix AZ
 1/2018-5/2019: Director, Down Syndrome Program, Barrow Neurological Institute,
Phoenix Children's Hospital, Phoenix AZ
 4/2018-: Professor of Neurology, Department of Neurology, Barrow Neurological Institute,
Phoenix Children's Hospital, Phoenix AZ
• 5/2018-: Director, Fragile X Syndrome Program, Barrow Neurological Institute,
Phoenix Children's Hospital, Phoenix AZ
• 12/2018-: Clinical Professor, Department of Neurology,
Creighton University School of Medicine, Omaha, NE
• 9/2019-: Professor of Pediatric Neurology, Mayo Clinic Alix School of Medicine, Scottsdale, AZ

Hospital Appointments

7/2005-6/2006: Shands Hospital, University of Florida, Gainesville, FL
7/2006-9/2011: Hermann Memorial Hospital, University of Texas Health Science Center, Houston, TX
12/2011-12/2017: University of Arkansas for Medical Sciences, Little Rock, AR
1/2012-12/2017: Arkansas Children's Hospital, Little Rock, AR
12/2017-: Phoenix Children's Hospital, Phoenix AZ

Medical Licenses

Arizona - 54974 - Active - 09/28/2017-12/15/2020
Arkansas - E7303 - Unlimited 12/02/2011-12/31/2018 (Inactive)
Kentucky - 51376 - 06/21/2018-02/28/2019 (Inactive
Texas - M5715 - Full Medical License - 03/12/2007-11/30/2017 (Inactive)

Honors and Awards

1991: Distinguished Service Award. Smell and Taste Research Center, University of Pennsylvania.
1991-1998: Ruggles Scholarship. Georgetown University Medical School, Washington, DC
1993-1996: Pre-Doctoral Fellowship. National Biomedical Research Foundation, Washington, D.C.
1994-1995: ARCS Award, Achievement Rewards for College Scientists Foundation, Washington, D.C..
1998: Lawrence S. Lilienfield, MD, PhD Award, Department of Physiology and Biophysics, Georgetown University Graduate School of Arts and Sciences
2003-2005: Charles King Foundation Post-Doctoral Fellowship, Medical Foundation, Boston, MA
2006: Nelson Butters Award, International Neuropsychological Society,Columbus, Ohio
2013: Arkansas Biomedical Institute New Investigator Award, University of Arkansas for
Medical Sciences, Little Rock AR
2018: Ranked #2 of the Top Ten Autism Research of 2018, Autism Speaks, New York NY 

Board Certifications

10/2004-9/2024: Board Certification in General Pediatrics
5/2004-4/2024: Board Certification in Neurology with Special Competence in Child Neurology
3/2016-3/2020: Certified Principal Investigator, Association of Clinical Research Professionals 

Specialized Coursework in Clinical Trials and Translational Research

2016: Advanced GCP: Assessing Compliance Risk, Association for Clinical Research
Professionals, Arkansas Children's Hospital, Little Rock, AR
2009: Clinical Trials. University of Texas Health Science Center, Houston, TX
2009: Navigating the Regulatory Highway. University of Texas Health Science Center, Houston, TX
2007: Translational Research. University of Texas Health Science Center, Houston, TX
2004: Introduction of Clinical Research, Children's Hospital Boston, Boston, MA

Specialized Training in Neuroimaging

2010: ANFI Bootcamp. University of Texas Health Science Center, Houston, TX
2005: Near-Infrared Spectroscopy-Diffuse Optical Imaging Visiting Fellowship,
MGH/MIT/HMS Martinos Imaging Center, Charlestown, MA
2003: Mini-Fellowship in Transcranial Magnetic Stimulation, Laboratory for Magnetic Brain
Stimulation, Beth-Israel Deaconess Medical Center, Boston, MA
2003: Siemens IDEA Software for Magnetic Resonance Sequence and Image Processing
Development Training, MGH/MIT/HMSMartinos Imaging Center, Charlestown, MA
2003: Basic and Advanced Magnoencepholography Operations and Data Analysis,
Martinos Imaging Center, Charlestown, MA
2003: fMRI Statistics, Martinos Imaging Center, Charlestown, MA

Specialized Training in Cognitive Neuroscience

2005: Summer Institute for Cognitive Neuroscience, Dartmouth College, Hanover, NH

Specialized Training in Autism Diagnosis and Screening

2008: Autism Diagnostic Observation Schedule Clinical and Research Training, University of Texas Health Science Center, Houston, TX
2019: RITA-T, Phoenix Children's Hospital, Phoenix AZ

Specialized Training in Complex and Non-linear System

1996: Complex Systems Summer School. Sante Fe Institute, Sante Fe, NM
1994: Noise Fluctuation Analysis: Characteristics of Ion-Channel Signal Ensemble. Department
of Physiology and Biophysics, Georgetown University, Washington, DC
1993: Origins of Order: Non-Linear Systems and Evolution. Department of Chemistry,Georgetown University, Washington, DC

Editorial Board

2020- : Journal of Translational Genetics and Genomics, Editorial Board
2019- : Annals of Translational Medicine, Editorial Board
2016- : Clinical Medicine Insights: Pediatrics, Editorial Board
2016- : Journal of Autism and Epilepsy, Editorial Board
2013- : American Journal of Neuroscience Research, Advisory Editorial Board
2013- : Frontiers in Child Health and Human Development, Associate Editor
2013-: Journal of Central Nervous System Disease, Editorial Board
2013- : Frontiers in Neuropsychiatric Imaging and Stimulation, Review Editorial Board
2012- : Scientific Reports Editorial Board
2012- : OA Autism, Advisory Board Member
2012- : The North American Journal of Medicine and Science, Editorial Board
2007- : Computers in Biology and Medicine, Editorial Board
2007: Journal of Pediatric Neurology, USA Editor
2005-2007: Computers in Biology and Medicine, Associate Editor
2006-2007: Journal of Pediatric Neurology, Assistant Editor

Publication Indices

h-index: 48
i10-index: 117
Citations: 8,005

Special Issue Guest Editor

Neuroconnectivity, Computers in Biology and Medicine, Dec 2011; Volume 41, Issue 12
 Mitochondrial, Metabolic and Nutritional Disorders Associated with Neurodevelopmental Disorders,Journal of Pediatric Biochemistry, Dec 2012; Volume 2, Issue 4.
 The Microbiome in Autism Spectrum Disorder, Microbial Ecology in Health and Disease, S1, 2015
 Metabolic and Immune Disorders Associated with Psychiatric Disease: Potential Etiology and Pathway for Treatment, Frontiers in Psychiatry, Section on Molecular Psychiatry, in press
 Comorbidity and Autism Spectrum Disorder, Frontiers in Psychiatry, Section on Child and Adolescent Psychiatry, in press.
 Secondary vs Idiopathic Autism, Frontiers in Psychiatry, Section on Child and Adolescent Psychiatry, in press.
 Advances in the Diagnosis and Treatment of Autism Spectrum Disorder: Part 1, Seminars in Pediatric Neurology, in press, expected May 2020.
 Advances in the Diagnosis and Treatment of Autism Spectrum Disorder: Part 2, Seminars in Pediatric Neurology, in press, expected September 2020.
Reviewer:
Acta Paediatrica, Autism Research, Biological Psychiatry, BMC Complementary and Alternative Medicine, BMC Psychiatry, Clinical Chemistry and Laboratory Medicine, Clinical Therapeutics, Developmental Cognitive Neuroscience, Developmental Medicine and Child Neurology, Developmental Neuroscience, Epilepsy Research, Environmental Science and Pollution Research, Expert Opinion On Therapeutic Targets, Genes, Frontiers in Child and Neurodevelopmental Psychiatry, Frontiers in Experimental Pharmacology and Drug Discovery, Frontiers in Epilepsy, Frontiers in Neuropsychiatric Imaging and Stimulation, Brain and Behavior, Headache, International Journal of Environmental Research and Public Health, International Journal of Molecular Sciences, Journal of Autism and Developmental Disorders, Journal of the International Neuropsychological Society, Journal of Neurochemistry, Journal of Neuroinflammation, Journal of Pediatric Infectious Disease, Journal of Psychosomatic Research, Molecular Basis of Disease, Molecular Psychiatry, Neurobiology of Aging, Neuroimage, Neurology, Neuropsychologia, Neuropsychopharmacology, Neuroscience and Biobehavioral Reviews, Neuroscience Letters, New England Journal of Medicine, Pediatrics, Prague Medical Report, Psychiatry Research, Redox Biology, Scientific Reports, Transactions on Biomedical Engineering

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